Primarily used on cotton. Registered as a U.S. pesticide in 1985. Reregistered in 2006. Currently under registration review.


Tribufos is used in 17 states.

Map of where the organophosphate pesticide tribufos is used in the 48 contiguous United States.

Tribufos is used in Alabama, Arizona, Arkansas, California, Florida, Georgia, Kansas, Louisiana, Mississippi, Missouri, New Mexico, North Carolina, Oklahoma, South Carolina, Tennessee, Texas, and Virginia.

Data is not available for Alaska, D.C., Hawaiʻi, and U.S. Territories. Data represents the most recent year available from USGS. Details.

See detailed maps of tribufos usage by state and county.

Human Health Effects

Even at low levels of exposure, tribufos can lead to serious negative health effects.


Neurodevelopmental Harm

High Risk Exposure Routes

People are exposed to tribufos through food and drinking water, even if they don’t live near areas where pesticides are sprayed. Details.

Food and/or Drinking Water

FarmworkersPeople performing post-application activities in previously treated fields, but do not directly apply pesticides themselves. Details.

Pesticide HandlersPeople involved in pesticide application process. Details.

Residential BystanderPeople who live near areas where pesticides are applied. Details.

Spray Drift

High Residue Foods

Where residue levels of tribufos exceeded allowable limits or were not legally allowed to have residues. Details.

[No high residue foods were specifically identified from the USDA’s PDP database.]

No detection does not necessarily mean there are no residues of concern. A relatively small sample of food products is tested and not all organophosphate pesticides are tested for.

Moreover, current U.S. pesticide tolerance levels are not protective against neurodevelopmental harm in children, so detections at or below tolerance levels do not indicate no harm.

Registered Uses

Where EPA allows tribufos to be used.


Additional Information

Estimated Use of Tribufos on Crops

Most recent agricultural crop usage data as provided by the U.S. Geographical Survey’s Pesticide National Synthesis Project. Does not reflect universal usage of tribufos. (How do EPest-low and EPest-high differ?)


EPest-low: Estimated use in millions of pounds of tribufos by year and crop.


EPest-high: Estimated use in millions of pounds of tribufos by year and crop.

U.S. Tolerances Categories & Commodities for Tribufos

The U.S. EPA sets maximum residue limits — known as “tolerances” — on the amount of tribufos that may remain in and on foods. The tolerance is the residue level that triggers enforcement actions.

Tolerances have been set for tribufos for: Milk Eggs Meat and/or Poultry. Maximum residue limits have been set for tribufos by the U.S. EPA for the following commodities: Cattle, Eggs, Goat, Hog, Horse, Milk, Poultry, Sheep

U.S. EPA Human Health Risk Assessments for Tribufos

Human Health Risk Assessments are conducted by the U.S. EPA to estimate the nature and probability of harmful health effects in people who may be exposed to pesticide. They are used to make informed decisions about approving new pesticides and new uses of registered pesticides, and during our regular review of existing pesticides. Read the assessment for tribufos.